Louis R Pasquale Selected Research

Nitric Oxide (Nitrogen Monoxide)

1/2019	Increased bioavailability of cyclic guanylate monophosphate prevents retinal ganglion cell degeneration.
1/2017	The Ability of Nitric Oxide to Lower Intraocular Pressure Is Dependent on Guanylyl Cyclase.
3/2016	Association of Dietary Nitrate Intake With Primary Open-Angle Glaucoma: A Prospective Analysis From the Nurses' Health Study and Health Professionals Follow-up Study.
1/2016	Is Estrogen a Therapeutic Target for Glaucoma?

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Louis R Pasquale Research Topics

Disease

80	Glaucoma 05/2024 - 09/2002
57	Open-Angle Glaucoma (Glaucoma, Open Angle) 12/2023 - 08/2003
12	Exfoliation Syndrome 01/2021 - 09/2010
9	Ganglion Cysts (Ganglion) 05/2024 - 01/2021
7	Angle-Closure Glaucoma (Glaucoma, Angle Closure) 01/2020 - 01/2012
5	Genetic Risk Score 03/2024 - 01/2017
5	Cataract (Cataracts) 01/2020 - 01/2014
5	Optic Nerve Diseases (Optic Neuropathy) 01/2019 - 09/2008
5	Ocular Hypertension (Glaucoma, Suspect) 09/2017 - 04/2008
4	Low Tension Glaucoma 05/2020 - 08/2011
4	Type 2 Diabetes Mellitus (MODY) 10/2019 - 01/2013
4	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2019 - 12/2015
3	Genetic Predisposition to Disease (Genetic Predisposition) 05/2024 - 01/2017
3	Diabetes Mellitus 03/2022 - 01/2014
3	Wounds and Injuries (Trauma) 01/2021 - 01/2014
3	Hypertension (High Blood Pressure) 12/2018 - 06/2011
2	Eye Diseases (Eye Disease) 01/2023 - 01/2019
2	Keratoconus 01/2023 - 01/2018
2	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2022 - 01/2022
2	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 06/2015
2	Neoplasms (Cancer) 01/2018 - 05/2012
2	Obesity 01/2017 - 05/2013
2	Atrophy 07/2008 - 04/2003
1	Hemorrhage 03/2024
1	Toothache (Toothaches) 03/2024
1	Reperfusion Injury 06/2023
1	Blindness (Hysterical Blindness) 11/2022
1	Optic Neuritis (Retrobulbar Neuritis) 11/2022
1	Optic Nerve Injuries 01/2021
1	Immune System Diseases (Immune Disorders) 01/2021
1	Retinal Arterial Macroaneurysm 01/2020

Drug/Important Bio-Agent (IBA)

36	Retinaldehyde (Retinal)IBA 05/2024 - 12/2007
8	Hormones (Hormone)IBA 12/2023 - 10/2007
7	Biomarkers (Surrogate Marker)IBA 05/2024 - 01/2014
6	SteroidsIBA 12/2023 - 01/2014
6	Estrogens (Estrogen)FDA Link 12/2023 - 08/2012
5	Caffeine (No Doz)FDA LinkGeneric 12/2023 - 05/2008
4	CholesterolIBA 01/2022 - 08/2016
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022 - 01/2019
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2013
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 01/2016
3	Gonadal Steroid Hormones (Sex Hormones)IBA 12/2023 - 01/2018
3	Oral ContraceptivesIBA 11/2022 - 01/2016
3	Coffee FDA Link 01/2021 - 09/2012
3	Bupropion (Wellbutrin)FDA LinkGeneric 01/2020 - 01/2012
3	Synthetic Prostaglandins (Prostaglandin Analogues)IBA 01/2018 - 09/2002
3	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 01/2016 - 02/2010
3	Brimonidine Tartrate (Alphagan)FDA LinkGeneric 07/2014 - 08/2011
3	Nitric Oxide Synthase (NO Synthase)IBA 06/2011 - 02/2010
2	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 10/2023 - 01/2020
2	EnzymesIBA 07/2023 - 01/2019
2	Folic Acid (Vitamin M)FDA LinkGeneric 02/2023 - 05/2014
2	Vitamin A (Retinol)FDA LinkGeneric 02/2023 - 08/2003
2	Dietary Fats (Dietary Fat)IBA 01/2023 - 05/2004
2	cytidylyl-(3'-5')-cytidine (CpC)IBA 01/2023 - 01/2022
2	trabecular meshwork-induced glucocorticoid response proteinIBA 01/2020 - 01/2019
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 01/2015
2	SolutionsIBA 01/2019 - 02/2015
2	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2019 - 03/2013
2	ClusterinIBA 01/2018 - 10/2015
2	betaglycan (TGFBR3)IBA 01/2017 - 07/2015
2	Ophthalmic Solutions (Eye Drops)IBA 03/2016 - 05/2007
2	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 10/2014 - 10/2014
2	ElastinIBA 10/2014 - 09/2010
2	Soluble Guanylyl CyclaseIBA 04/2013 - 01/2013
2	ArgonIBA 07/2006 - 01/2005
1	Dietary SodiumIBA 05/2024
1	SodiumIBA 05/2024
1	RNA (Ribonucleic Acid)IBA 01/2024
1	GlucocorticoidsIBA 12/2023
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2023
1	Antihypertensive Agents (Antihypertensives)IBA 10/2023
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 09/2023
1	Thioredoxin Reductase 2IBA 07/2023
1	Triglycerides (Triacylglycerol)IBA 01/2023
1	IonsIBA 01/2023
1	DiglyceridesIBA 01/2023
1	ZincIBA 01/2023
1	CopperIBA 01/2023
1	Cadherins (E-Cadherin)IBA 01/2023
1	Branched-Chain Amino AcidsIBA 05/2022
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2021
1	Protein AggregatesIBA 01/2021
1	Ginkgo biloba extract (Rokan)IBA 05/2020
1	Adrenergic Agonists (Adrenergic Receptor Agonist)IBA 01/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020
1	CannabinoidsIBA 01/2020
1	Cholinergic Antagonists (Anticholinergics)IBA 01/2020

Therapy/Procedure

11	Trabeculectomy (Trabeculoplasty) 01/2022 - 09/2002
11	Lasers (Laser) 01/2022 - 09/2002
9	Therapeutics 11/2022 - 01/2008
2	Slit Lamp 01/2021 - 06/2014
2	Glaucoma Drainage Implants 10/2018 - 01/2007
2	Phacoemulsification 08/2017 - 01/2017
2	Filtering Surgery 01/2017 - 01/2015
2	Ovariectomy (Oophorectomy) 01/2016 - 04/2014
1	Dental Restoration Wear 03/2024
1	Diet Therapy (Therapy, Diet) 01/2023
1	Postoperative Care 11/2022
1	Ambulatory Care (Outpatient Care) 01/2022